Diabetes mellitus impact on left ventricular assist device outcomes in heart failure patients: National Inpatient Sample study.
Omar ObeidatAbdullah H AbdullahiZeeshan IsmailMohamed F IsmailHamza AlzghoulMohammed TarawnehRabab ElsadekHashim Al-AniNatalie P HurlockAndrew L SmockPublished in: Future cardiology (2023)
Aim: Diabetes mellitus (DM) is a recognized risk factor for heart failure (HF), increasing the likelihood of requiring left ventricular assist device (LVAD) therapy. Objective: This retrospective cohort study aims to assess the impact of DM on LVAD patients, focusing on in-hospital mortality as the primary outcome. Methods: Utilizing the National Inpatient Sample administrative database, data from 11,506 adult HF patients who underwent LVAD implantation were analyzed. Results: Of the patients, 44.28% had diabetes. Adjusting for various factors, diabetic patients exhibited shorter hospital stays, lower admission costs and similar in-hospital mortality rates compared with non-diabetic patients. Conclusion: These findings enhance our understanding of the risks and benefits of LVAD therapy in patients with refractory HF and DM.
Keyphrases
- left ventricular assist device
- end stage renal disease
- ejection fraction
- heart failure
- newly diagnosed
- chronic kidney disease
- prognostic factors
- type diabetes
- palliative care
- peritoneal dialysis
- mental health
- stem cells
- healthcare
- emergency department
- cardiovascular disease
- risk assessment
- left ventricular
- young adults
- climate change
- acute heart failure
- insulin resistance
- atrial fibrillation
- acute care
- adverse drug