Maternal pre-pregnancy overweight or obesity and risk of birth defects in offspring: Population-based cohort study.
Weiying LiuLuzhong RenFang FangRuoqing ChenPublished in: Acta obstetricia et gynecologica Scandinavica (2024)
Maternal pre-pregnancy overweight or obesity was associated with a higher risk of birth defects, particularly congenital malformations of the circulatory system, in offspring. Gestational diabetes interacts additively with pre-pregnancy overweight or obesity on modifying the risk of congenital malformations of the circulatory system. The importance of improving weight management and assessment of glucose and metabolic functions was emphasized among women planning for pregnancy who are overweight or obese.
Keyphrases
- pregnancy outcomes
- weight loss
- weight gain
- bariatric surgery
- pregnant women
- birth weight
- metabolic syndrome
- physical activity
- body mass index
- insulin resistance
- preterm birth
- type diabetes
- high fat diet
- glycemic control
- adipose tissue
- high fat diet induced
- extracorporeal membrane oxygenation
- obese patients
- polycystic ovary syndrome
- blood pressure