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Automatic Evaluation for Bioengineering of Human Artificial Ovary: A Model for Fertility Preservation for Prepubertal Female Patients with a Malignant Tumor.

Wanxue WangCheng PeiEvgenia IsachenkoYang ZhouMengying WangGohar RahimiWensheng LiuPeter MallmannVolodimir Isachenko
Published in: International journal of molecular sciences (2022)
The novel artificial ovary-enabled primordial follicles to enter the growth cycle after activation and grow into secondary follicles. The use of a fibrin scaffold as a carrier preserves the developmental potential of primordial germ cells and is a potentially effective method for preserving fertility in prepubertal girls.
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