Environmental and genetic risk factors associated with total knee arthroplasty following cruciate ligament surgery.
Paul M InclanRobert H BrophyNancy L SacconeYinjiao MaVy PhamElizabeth L YanikPublished in: The bone & joint journal (2024)
Patients with a history of prior cruciate ligament surgery have substantially higher risk of TKA and undergo arthroplasty at a relatively younger age than individuals without a history of prior cruciate ligament surgery. Physically demanding work and obesity were associated with higher odds of TKA after cruciate ligament surgery, but no SNP was associated with risk of TKA.
Keyphrases
- total knee arthroplasty
- total hip
- minimally invasive
- coronary artery bypass
- surgical site infection
- type diabetes
- metabolic syndrome
- insulin resistance
- percutaneous coronary intervention
- dna methylation
- physical activity
- weight gain
- coronary artery disease
- skeletal muscle
- human health
- climate change
- atrial fibrillation