Concentrations of psychoactive substances in blood samples from non-fatal and fatal opioid overdoses.

Hilde Marie Erøy EdvardsenCarl AamodtStig Tore Bogstrand Peter Krajci Vigdis Vindenes Eline Borger Rognli

Published in: British journal of clinical pharmacology (2022)

The total load of drug concentrations was associated with the fatal outcome of an overdose, while the number of drugs used, to a lesser extent, differentiated between those who survived and those who died from an overdose. Higher opioid concentrations were associated with treatment with higher naloxone doses.

Keyphrases

chronic pain
pain management
emergency department
drug induced
combination therapy
adverse drug
electronic health record