PARVB and HSD17B13 variants are associated with nonalcoholic fatty liver disease in children.

Kyung Jae Lee Jin Soo Moon Jin Gyu Lim Homin Huh Jeong Eun Ahn Lia KimNan Young KimJeong Kee Seo

Published in: Journal of gastroenterology and hepatology (2024)

HSD17B13 has protective effects on the severity of pediatric nonalcoholic fatty liver disease. Variants of HSD17B13, PARVB, PNPLA3, SAMM50, and TM6SF2 had an additive effect on nonalcoholic fatty liver disease.

Keyphrases

copy number
liver fibrosis
gene expression
dna methylation