Identification and characterization of the first endogenous phospholipase A2 inhibitor from a non-venomous tropical snake, Boa constrictor (Serpentes: Boidae).

Consuelo Latorre Fortes-DiasDiego Henrique Fagundes MacedoRafaella Pereira BarbosaGabriel Souza-SilvaPaula Ladeira Ortolani

Published in: The journal of venomous animals and toxins including tropical diseases (2020)

A functional sbγPLI (BcNF) was described in the blood plasma of B. constrictor. BcNF displayed higher primary identity with sbγPLIs from Viperidae than to sbγPLIs from non-venomous species from Asia. The physiological role played by sbγPLIs in non-venomous snake species remains to be understood. Further investigation is needed.

Keyphrases

climate change
genetic diversity