The presence of SARS-CoV-2 in multiple clinical specimens of a fatal case of COVID-19: a case report.
Liba SokolovskaAnna Terentjeva-DecukaMaksims CistjakovsZaiga Nora-KrukleSabine GravelsinaAnda VilmaneKatrine VecvagareModra MurovskaPublished in: Journal of medical case reports (2022)
The various cardiovascular, autoimmune, and oncological disorders, advanced age, and the high levels of inflammatory markers predisposed the patient to severe COVID-19 and determined the fatal outcome of the disease. We believe that the multiple specimen SARS-CoV-2 positivity and extremely high viral loads in nasopharyngeal swab and fecal samples to be the result of COVID-19 severity, the inability of viral clearance and weakened immune response due to advanced age, comorbidities, and the presence of non-Hodgkin's lymphoma and the immunosuppressive treatment for it, highlighting the risks of COVID-19 in such patients.
Keyphrases
- sars cov
- respiratory syndrome coronavirus
- coronavirus disease
- immune response
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- multiple sclerosis
- diffuse large b cell lymphoma
- prognostic factors
- peritoneal dialysis
- dendritic cells
- toll like receptor
- rectal cancer
- minimally invasive
- inflammatory response
- climate change
- radical prostatectomy
- fine needle aspiration