The oral histopathological and immunological characteristics of a xenogeneic mouse chronic graft-versus-host disease model.
Qiaozhi JiangXiangzhi YongZhenmin LiuYuxi ZhouGuocheng MeiQianming ChenTiantian WuRenchuan TaoPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2021)
Inflammation in oral mucosa epithelium and salivary glands, and CD4+ and CD8+ T cells dominating infiltration are the main oral features in the xenogeneic cGVHD mouse model. The severity of oral histopathological lesions shows a dose and time correlation. These may be helpful to oral cGVHD research.
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