Antidotal Sodium Bicarbonate Therapy: Delayed QTc Prolongation and Cardiovascular Events.
Siri ShastryJudson EllisGeorge LooRajesh VedanthanLynne D RichardsonAlex F ManiniPublished in: Journal of medical toxicology : official journal of the American College of Medical Toxicology (2020)
In ED patients with acute drug overdose and potential indications for SBT, administration of SBT as part of routine clinical care was an independent, dose-dependent, predictor of ACVE, DQTP, and death. This study was not designed to determine whether the SBT or acute overdose itself was causative of ACVE; however, these data suggest that poisoned patients receiving antidotal SBT require close cardiovascular monitoring.
Keyphrases
- cardiovascular events
- drug induced
- coronary artery disease
- emergency department
- cardiovascular disease
- healthcare
- liver failure
- palliative care
- respiratory failure
- electronic health record
- clinical practice
- big data
- quality improvement
- type diabetes
- risk assessment
- machine learning
- hepatitis b virus
- pain management
- chronic pain
- extracorporeal membrane oxygenation
- mesenchymal stem cells
- acute respiratory distress syndrome
- climate change