Complete Genome Sequence of Herpes Simplex Virus 1 Strain McKrae.

Xiaoli JiaoHongyan SuiChristopher LyonsBao TranBrad T ShermanTomozumi Imamichi

Published in: Microbiology resource announcements (2019)

Herpes simplex virus 1 (HSV-1) strain McKrae is highly virulent and relatively neuroinvasive in animal models compared with other wild-type HSV-1 strains. To identify the genetic determinants that lead to the unique phenotypes of the McKrae strain, we sequenced its genome with PacBio single-molecule real-time (SMRT) technology and resolved the complete sequence.

Keyphrases

herpes simplex virus
single molecule
wild type
genome wide
escherichia coli
atomic force microscopy
living cells
gene expression
copy number
fluorescent probe