Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann-Pick disease type C treatment.
Yusei YamadaMadoka Fukaura-NishizawaAsami NishiyamaAkira IshiiTatsuya KawataAina ShirakawaMayuko TanakaYuki KondoToru TakeoNaomi NakagataToru MiwaHiroki TakedaYorihisa OritaKeiichi MotoyamaTaishi HigashiHidetoshi ArimaTakahiro SekiYuki KurauchiHiroshi KatsukiKatsumi HigakiKentaro MinamiNaoki YoshikawaRyuji IkedaMuneaki MatsuoTetsumi IrieYoichi IshitsukaPublished in: Clinical and translational medicine (2023)
Our findings highlight the importance of strategies for optimizing the molecular structure of CDs to overcome this functional dilemma in the treatment of NPC.
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