Synthesis and In Vitro and In Vivo Evaluation of [3H]LRRK2-IN-1 as a Novel Radioligand for LRRK2.
Noeen MalikAndrew N GiffordJohan SandellDaniel TuchmanYu-Shin DingPublished in: Molecular imaging and biology (2018)
The high LRRK2 brain density observed in our study suggests the feasibility for positron emission tomography imaging of LRRK2 (a potential target) with radioligands of higher affinity and specificity.