Login / Signup

Leucocyte- and Platelet-Rich Fibrin Block: Its Use for the Treatment of a Large Cyst with Implant-Based Rehabilitation.

Rodolfo MauceriDenise MurgiaOrazio CiceroLuigi PaternòLuca FiorilloViviana De CaroGiuseppina Campisi
Published in: Medicina (Kaunas, Lithuania) (2021)
The management of critical-size bone defects is still demanding. Recently, autologous platelet concentrates in combination with bone substitute have been applied and reported in a few studies. Our aim is to report the healing of a critical-size alveolar bone defect treated with a new bone regeneration technique by means of L-PRF and L-PRF blocks. A 45-year-old woman presented a large cystic lesion; the extraction of three teeth, a cyst removal procedure, and bone regeneration procedures with L-PRF and L-PRF blocks were planned. The L-PRF block was prepared by mixing a bone substitute with a piece of L-PRF membrane and liquid fibrinogen. Additionally, after bone healing an implant-based rehabilitation was optimally performed. On the basis of the positive results, in terms of bone healing and tissue regeneration in a large bone defect, the application of L-PRF and L-PRF blocks, in agreement with the scarce literature, is suggested as a feasible procedure in selected cases.
Keyphrases
  • bone regeneration
  • bone mineral density
  • soft tissue
  • bone loss
  • stem cells
  • postmenopausal women
  • body composition
  • minimally invasive
  • mesenchymal stem cells