Effects of moderate and severe hypocapnia on intracerebral perfusion and brain tissue oxygenation in piglets.

Simone Katja Ringer Nicola Groes ClaussenNelly SpielmannMarkus Weiss

Published in: Paediatric anaesthesia (2019)

This animal model revealed reduced cerebral blood flow and brain tissue oxygenation during hypocapnia without detectable changes in regional oxygen saturation as measured by NIRS. Changes occurred as early as during moderate hypocapnia.

Keyphrases

cerebral blood flow
resting state
white matter
high intensity
functional connectivity
blood flow
cerebral ischemia
single cell
magnetic resonance imaging
multiple sclerosis
subarachnoid hemorrhage
blood brain barrier