Identification of Potential TMPRSS2 Inhibitors for COVID-19 Treatment in Chinese Medicine by Computational Approaches and Surface Plasmon Resonance Technology.

Rong YangLinhua LiuDansheng JiangLei LiuHuili YangHongling XuMeirong QinPing WangJiangyong Gu Yu-Feng Xing

Published in: Journal of chemical information and modeling (2023)

Specific active compounds including narirutin, saikosaponin B1, and rutin in CM recipes potentially target and inhibit TMPS2, probably exerting a therapeutic effect on COVID-19.

Keyphrases

coronavirus disease
sars cov
respiratory syndrome coronavirus
combination therapy
climate change
risk assessment