Gene expression profiling identifies two chordoma subtypes associated with distinct molecular mechanisms and clinical outcomes.
Jiwei BaiJianxin ShiYazhuo ZhangChuzhong LiYujia XiongHela KokaDifei WangTongwu ZhangLei SongWen LuoBin ZhuBelynda D HicksAmy A HutchinsonErin L KirkMelissa A TroesterMingxuan LiYutao ShenTianshun MaJunmei WangXing LiuShuai WangSong-Bai GuiMary Lou McMasterStephen J ChanockDilys M ParryAlisa M GoldsteinXiaohong R YangPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Our findings may improve the understanding of subtype-specific tumorigenesis of chordoma and inform clinical prognostication and targeted options.