Presented in the article are the generalized data of the Russian and foreign literature addressing the currently important problem of myocardial ruptures as one of the most dangerous complications of infarction, also analysing the results of clinical studies on interconnection of heart ruptures with systemic thrombolytic therapy and with a percutaneous coronary intervention. This is followed by describing the mechanisms that may lead to myocardial rupture during thrombolytic therapy and surgical endovascular treatment, underlying the necessity of pharmacological pre- and post-conditioning for prevention of reperfusion myocardial lesions. The article also touches upon the clinical and instrumental diagnosis of myocardial ruptures, as well as approaches to surgical treatment depending on the type of rupture and necessity of myocardial revascularization.
Keyphrases
- left ventricular
- acute myocardial infarction
- percutaneous coronary intervention
- endovascular treatment
- st segment elevation myocardial infarction
- systematic review
- pulmonary embolism
- acute ischemic stroke
- acute coronary syndrome
- st elevation myocardial infarction
- stem cells
- coronary artery disease
- coronary artery bypass grafting
- antiplatelet therapy
- machine learning
- atrial fibrillation
- mesenchymal stem cells
- big data
- brain injury
- cell therapy
- subarachnoid hemorrhage