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Morphology-based deep learning enables accurate detection of senescence in mesenchymal stem cell cultures.

Liangge HeMingzhu LiXinglie WangXiaoyan WuGuanghui YueTianfu WangYan ZhouBaiying LeiGuangqian Zhou
Published in: BMC biology (2024)
This deep learning has been applied for the first time to detect senescent MSCs, showing promising performance in both chronic and acute MSC senescence. The system can be a labor-saving and cost-effective option for screening MSC culture conditions and anti-aging drugs, as well as providing a powerful tool for non-invasive and real-time morphological image analysis integrated into cell production.
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