Use of Morphometric Mapping to Characterise Symptomatic Chiari-Like Malformation, Secondary Syringomyelia and Associated Brachycephaly in the Cavalier King Charles Spaniel.
Susan Penelope KnowlerChloe CrossSandra GriffithsAngus K McFadyenJelena JovanovikAnna TauroZoha KibarColin J DriverRoberto M La RagioneClare RusbridgePublished in: PloS one (2017)
Morphometric mapping provides a diagnostic tool for quantifying symptomatic CM, secondary SM and their relationship with brachycephaly. It is hypothesized that CM pain is associated with increased brachycephaly and SM can result from different combinations of abnormalities of the forebrain, caudal fossa and craniocervical junction which compromise the neural parenchyma and impede cerebrospinal fluid flow.