Cytokine-Laden Extracellular Vesicles Predict Patient Prognosis after Cerebrovascular Accident.

Anthony FringuelloPhilip D TatmanTadeusz H WroblewskiJohn A ThompsonXiaoli YuKevin O LilleheiRobert G KowalskiMichael W Graner

Published in: International journal of molecular sciences (2021)

These findings correlate plasma-derived EV cytokine content with detrimental outcomes after stroke, highlighting the potential for EVs to provide cytokines with a means of long-range delivery of inflammatory signals that perpetuate neuroinflammation after stroke, thus hindering recovery.

Keyphrases

case report
traumatic brain injury
oxidative stress
lipopolysaccharide induced
cognitive impairment
type diabetes
cerebral ischemia
metabolic syndrome
inflammatory response
adipose tissue
subarachnoid hemorrhage