Azithromycin to Reduce Mortality - An Adaptive Cluster-Randomized Trial.

Kieran S O'BrienAhmed M ArzikaAbdou AmzaRamatou MalikiBawa AichatouIsmael Mamane BelloDiallo BeidiNasser GaloNaser HarounaAlio M KarambaSani MahamadouMoustapha AbarchiAlmou IbrahimElodie LebasBrittany PetersonZijun LiuVictoria LeEmily ColbyThuy DoanJeremy D KeenanCatherine E OldenburgTravis C PorcoBenjamin F ArnoldThomas M Lietmannull null

Published in: The New England journal of medicine (2024)

Azithromycin distributions to children 1 to 59 months of age significantly reduced mortality and was more effective than treatment of infants 1 to 11 months of age. Antimicrobial resistance must be monitored. (Funded by the Bill and Melinda Gates Foundation; AVENIR ClinicalTrials.gov number, NCT04224987.).

Keyphrases

antimicrobial resistance
cardiovascular events
risk factors
young adults
type diabetes
combination therapy