Systemic inflammation and symptomatology in patients with prostate cancer treated with androgen deprivation therapy: Preliminary findings.
Aasha I HooglandHeather S L JimBrian D GonzalezBrent J SmallDanielle GilvaryElizabeth C BreenJulienne E BowerMayer FishmanBabu ZachariahPaul B JacobsenPublished in: Cancer (2020)
Results of this preliminary study suggest that increases in circulating IL-6, perhaps due to testosterone inhibition, may play a role in fatigue secondary to receipt of ADT. Additional research is needed to determine whether interventions to reduce circulating inflammation improve fatigue in this population.