Adrenarche and pubarche in girls with turner syndrome during growth-promoting therapy with human growth hormone.
Helmuth-Günther DörrTheresa PengerMichaela MarxManfred RauhPatricia G OppeltThomas K M VölklPublished in: BMC endocrine disorders (2019)
The onset of adrenarche in girls with TS undergoing GH therapy does not differ from that in healthy girls. However, adrenarche is more pronounced in girls with TS. There is no difference in DHEAS levels between the TS girls with spontaneous puberty and the TS girls with primary ovarian insufficiency (POI), while the tempo of pubarche is markedly slower in the girls with POI.