Plasma heparin cofactor II activity is inversely associated with albuminuria and its annual deterioration in patients with diabetes.

Tomoyo HaraRyoko UemotoAkiko SekineYukari MitsuiShiho MasudaKiyoe KurahashiSumiko YoshidaToshiki OtodaTomoyuki YuasaAkio KurodaYasumasa IkedaItsuro EndoSoichi HondaKatsuhiko YoshimotoAkira KondoToshiaki TamakiToshio MatsumotoMunehide MatsuhisaMasahiro AbeKen-Ichi Aihara

Published in: Journal of diabetes investigation (2021)

The plasma HCII activity was inversely and specifically associated with glomerular injury in patients with diabetes. The results suggest that HCII can serve as a novel predictive factor for early-stage DKD development, as represented by albuminuria.

Keyphrases

early stage
venous thromboembolism
squamous cell carcinoma
lymph node
sentinel lymph node
rectal cancer