Dynamic time domain near-infrared optical tomography based on a SPAD camera.

Jingjing JiangAldo Di Costanzo MataScott LindnerEdoardo CharbonMartin WolfAlexander Kalyanov

Published in: Biomedical optics express (2020)

In many clinical applications it is relevant to observe dynamic changes in oxygenation. Therefore the ability of dynamic imaging with time domain (TD) near-infrared optical tomography (NIROT) will be important. But fast imaging is a challenge. The data acquisition of our handheld TD NIROT system based on single photon avalanche diode (SPAD) camera and 11 light sources was consequently accelerated. We tested the system on a diffusive medium simulating tissue with a moving object embedded. With 3D image reconstruction, the moving object was correctly located using only 0.2 s exposure time per source.

Keyphrases

high resolution
high speed
working memory
convolutional neural network
deep learning
drinking water
electron microscopy