Chondrotoxicity of Local Anesthetics: Liposomal Bupivacaine Is Less Chondrotoxic than Standard Bupivacaine.

Travis FarmerS Craig MorrisRobert QuigleyNirav H AminMontri D WongworawatHasan M Syed

Published in: Advances in pharmacological and pharmaceutical sciences (2020)

Bupivacaine and liposomal bupivacaine are both toxic to chondrocytes. Liposomal bupivacaine is less chondrotoxic than standard bupivacaine and does not demonstrate a time-dependent toxicity.

Keyphrases

postoperative pain
pain management
oxidative stress
chronic pain