Neuropsychological, behavioral, and quality-of-life outcomes in children and adolescents with sickle cell disease treated with nonmyeloablative matched sibling donor hematopoietic cell transplantation: A case series.

Taryn B Fay-McClymont Dania A MonagelGurpreet SinghFiona SchulteBrian L BrooksWilliam S MacAllisterNaddley DésiréAleksandra MineykoMarsha VassermanMichael T LeakerTony H TruongRavi ShahVictor A LewisKeith Owen YeatesGregory M T Guilcher

Published in: Pediatric blood & cancer (2022)

Neuropsychological functioning in a sample of children and adolescents treated uniformly with NMA MSD HCT remained stable or improved in most cognitive domains, and improvements in quality of life and family functioning were observed.

Keyphrases

mild cognitive impairment
type diabetes
metabolic syndrome
signaling pathway
cell death
cell proliferation
weight loss
glycemic control