Vitamin B 12 plays a significant role in maintaining human health. Deficiency or excess intake of vitamin B 12 may cause some diseases. Therefore, it is significant to fabricate sensors for sensitive assay of vitamin B 12 . In the past few years, a variety of nanomaterials have been developed for the fluorescence detection of vitamin B 12 in tablets, injection, human serum and food. In the review, the assay mechanisms of fluorescent nanomaterials for sensing vitamin B 12 were first briefly discussed. And the progress of various nanomaterials for fluorescence detection of vitamin B 12 were systematically summarized. Furthermore, the sensing performance of fluorescent nanosensors was compared with fluorescent probes. Lastly, the challenges and perspectives about the topic were presented.
Keyphrases
- label free
- living cells
- human health
- quantum dots
- single molecule
- risk assessment
- loop mediated isothermal amplification
- real time pcr
- high throughput
- fluorescent probe
- energy transfer
- climate change
- small molecule
- sensitive detection
- ultrasound guided
- fluorescence imaging
- weight gain
- replacement therapy
- smoking cessation