Nanostructured Polyoxometalate-Based Heterogeneous Electrode Materials for Electrochemical Sensing of Glucose.

We exploited a tactic to obtain a low-cost, high-efficiency, pollution-free, and stable nonenzymatic polyoxometalate-based heterogeneous electrode material for electrochemical sensing of glucose. It is first followed by the countercation exchange of K 2 Na 8 [Cu 4 (H 2 O) 2 (PW 9 O 34 ) 2 ] ( CuPOM ) using cesium chloride to prepare an insoluble CuPOM ( Cs-CuPOM ), which exhibits a uniform and perfect claviform shape with smooth surface. Further, it was mixed with graphite powder to prepare Cs-CuPOM- modified carbon paste electrode ( Cs-CuPOM/CPE ) with the Cs-CuPOM content between 15% and 50% in weight. This obtained electrode material Cs-CuPOM shows a better electrochemical sensor activity than Cs-MnPOM , Cs-FePOM, and other reported POM-based electrode materials for glucose oxidation on account of their quicker electron transfer kinetics, which also exhibits conspicuous characteristics with a wide linear range of 5-1500 μM. It also possesses a high sensitivity of 16.3 A M -1 cm -2 and a low limit of detection (LOD) of 0.99 × 10 -6 M at the signal-to-noise ratio of 3. The conspicuous sensing feature, low cost, and liable synthetic method can make Cs-CuPOM a promising candidate for the exploitation of a preeminent glucose sensor.