Sedation practices and clinical outcomes in mechanically ventilated patients in a prospective multicenter cohort.
Romina E AragónAlvaro ProañoNicole MongilardiAldo de FerrariPhabiola HerreraRollin RoldanEnrique PazAmador A JaymezEduardo ChirinosJose PortugalRocio QuispeRoy G BrowerWilliam CheckleyPublished in: Critical care (London, England) (2019)
Deep sedation, agitation, and cumulative dose of benzodiazepines were all independently associated with higher 90-day mortality. Additionally, deep sedation was associated with less ventilator-, ICU-, and hospital-free days. In contrast, haloperidol was associated with lower mortality in our study.
Keyphrases
- mechanical ventilation
- intensive care unit
- acute respiratory distress syndrome
- healthcare
- end stage renal disease
- cardiovascular events
- newly diagnosed
- ejection fraction
- primary care
- magnetic resonance
- prognostic factors
- clinical trial
- emergency department
- cardiovascular disease
- patient reported outcomes
- acute care
- adverse drug