HPMA-PLGA Based Nanoparticles for Effective In Vitro Delivery of Rifampicin.

Sarita RaniAvinash GothwalPawan K PandeyDevendra S ChauhanPraveen K PachouriUmesh D GuptaUmesh Gupta

Published in: Pharmaceutical research (2018)

The pathogen inhibition studies revealed that developed HPR-NPs were approximately four times more effective with (p < 0.05) than pure drug against sensitive Mycobacterium tuberculosis (MTB) stain. It may be concluded that HPR-NPs holds promising potential for increasing solubility and bioavailability of RMP.

Keyphrases

mycobacterium tuberculosis
pulmonary tuberculosis
drug delivery
oxide nanoparticles
single cell
emergency department
case control
risk assessment
climate change