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Low-Dose Immunotherapy in Head and Neck Cancer: A Randomized Study.

Vijay Maruti PatilVanita NoronhaNandini Sharrel MenonRahul RaiAtanu BhattacharjeeAjay SinghKavita NawaleShweta JogdhankarRupali TambeSachin DhumalRiddhi SawantMitali AloneDevanshi KarlaZoya PeelayShruti PathakArun BalajiSuman KumarNilendu PurandareArchi AgarwalAmeya D PuranikAbhishek MahajanAmit JanuGunjesh Kumar SinghNeha MittalSubhash YadavShripad D BanavaliKumar Prabhash
Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
To our knowledge, this is the first-ever randomized study to demonstrate that the addition of low-dose nivolumab to metronomic chemotherapy improved OS and is an alternative standard of care for those who cannot access full-dose checkpoint inhibitors.
Keyphrases
  • low dose
  • healthcare
  • high dose
  • dna damage
  • palliative care
  • cell cycle
  • quality improvement
  • locally advanced
  • squamous cell carcinoma
  • rectal cancer