Characteristics of high-dose benzodiazepine use: nationwide cohort study on new benzodiazepine users with 5-year follow-up.

Hanna Särkilä Heidi TaipaleAntti TanskanenTerhi KurkoTero TaiminenJari TiihonenReijo SundLeena SaastamoinenJarmo Hietala Solja Niemelä

Published in: BJPsych open (2024)

Clinicians should be aware of the dose escalation risk especially when prescribing diazepam, alprazolam or clonazepam for psychiatric indications. If BZDRs are needed, our findings suggest favouring oxazepam.

Keyphrases

high dose
primary care
low dose
mental health
stem cell transplantation
palliative care
open label
emergency department
clinical trial
adverse drug
double blind