Levodopa Rescues Retinal Function in the Transgenic A53T Alpha-Synuclein Model of Parkinson's Disease.
Katie K N TranVickie H Y WongKirstan A VesseyDavid Isaac FinkelsteinBang V BuiChristine T O NguyenPublished in: Biomedicines (2024)
These findings deepen our understanding of dopamine and alpha-synuclein interactions in the retina and provide a high-throughput preclinical framework, primed for translation, through which novel therapeutic compounds can be objectively screened and assessed for fast-tracking PD drug discovery.