Focal adhesion kinase-related pathways may be suppressed by metformin in vascular smooth muscle cells in high glucose conditions.

Ali Akbar SoleimaniGhasem GhasmpourAsghar MohammadiMasoomeh GholizadehBorhan Rahimi AbkenarMohammad Najafi

Published in: Endocrinology, diabetes & metabolism (2022)

The results showed that metformin may suppress the proliferation and migration of VSMCs via FAK-related pathways and may retard the progression of vessel stenosis in diabetes.

Keyphrases

vascular smooth muscle cells
high glucose
endothelial cells
angiotensin ii
type diabetes
cardiovascular disease
cell migration
glycemic control
escherichia coli
tyrosine kinase
skeletal muscle
staphylococcus aureus
biofilm formation