Beta cell function and insulin sensitivity in youth with early type 1 diabetes from a two-hour 7-sample OGTT.

The 2-h 7-point OGTT is reliable in subjects with Stage 1 T1D for assessment of β-cell responsiveness, insulin sensitivity, and disposition index. Incorporation of these analyses into current 2-h diabetes staging and monitoring OGTTs offers the potential to more accurately quantify risk of progression in the early stages of T1D.