Renal dysfunction by baseline CD4 cell count in a cohort of adults starting antiretroviral treatment regardless of CD4 count in the HIV Prevention Trials Network 071 [HPTN 071; Population Effect of Antiretroviral Therapy to Reduce HIV Transmission (PopART)] study in South Africa.
Peter BockK NelG FattiR SlootN FordJ VogetC GunstN GrobbelaarF LouisS FloydR HayesH AylesN BeyersS Fidlernull nullPublished in: HIV medicine (2019)
This study showed low rates of renal dysfunction at baseline and on ART, with lower rates of baseline renal dysfunction among individuals with baseline CD4 counts > 200 cells/μL. Strategies that use baseline characteristics, such as age, to identify individuals at high risk of renal dysfunction on ART for enhanced eGFR monitoring may be effective and should be the subject of future research.
Keyphrases
- antiretroviral therapy
- hiv infected
- hiv positive
- human immunodeficiency virus
- hiv aids
- hiv infected patients
- south africa
- oxidative stress
- small cell lung cancer
- peripheral blood
- induced apoptosis
- hepatitis c virus
- stem cells
- men who have sex with men
- current status
- cell proliferation
- smoking cessation
- bone marrow
- cell cycle arrest