Synergetic Influence of Bismuth Oxide Nanoparticles, Cisplatin and Baicalein-Rich Fraction on Reactive Oxygen Species Generation and Radiosensitization Effects for Clinical Radiotherapy Beams.

Noor Nabilah Talik Sisin Khairunisak Abdul Razak Safri Zainal Abidin Nor Fazila Che Mat Reduan Abdullah Raizulnasuha Ab Rashid Muhammad Afiq Khairil Anuar Wan Nordiana Rahman

Published in: International journal of nanomedicine (2020)

The BiONPs, Cis and BRF are the potential radiosensitizers that could improve the efficiency of radiotherapy to eradicate the cancer cells. The combination of these potent radiosensitizers might produce multiple effects when applied in radiotherapy. The BC combination is found to have the highest SER, followed by the BCB combination. This study is also the first to investigate the effect of BRF in combination with BiONPs (BB) and BC (BCB) treatments.

Keyphrases

early stage
oxide nanoparticles
locally advanced
reactive oxygen species
radiation therapy
radiation induced
growth factor
rectal cancer
anti inflammatory