Do young adolescents with first-episode psychosis or ADHD show sensorimotor gating deficits?

Jacob Rydkjaer Jens Richardt Moellegaard JepsenAnne Katrine PagsbergBirgitte FagerlundBirte Yding GlenthoejBob Oranje

Published in: Psychological medicine (2019)

Young adolescents with SZ showed sensorimotor gating deficits similar to those usually found in adults with SZ and had larger startle magnitude than patients with other types of non-affective early-onset psychosis. No sensorimotor gating deficits were found in adolescents with ADHD. Our findings support the theory that deficient PPI is endophenotypic for SZ.

Keyphrases

early onset
young adults
attention deficit hyperactivity disorder
traumatic brain injury
physical activity
functional connectivity
autism spectrum disorder
late onset
working memory
middle aged