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Impact of somatic mutations on prognosis in resected non-small-cell lung cancer: The Japan Molecular Epidemiology for lung cancer study.

Akihiro TamiyaYasuhiro KohShun-Ichi IsaAkihito KuboMasahiko AndoHideo SakaNaoki YoshimotoSadanori TakeoHirofumi AdachiTsutomu TagawaOsamu KawashimaMotohiro YamashitaKazuhiko KataokaMitsuhiro TakenoyamaYukiyasu TakeuchiKatsuya WatanabeAkihide MatsumuraTomoya Kawaguchi
Published in: Cancer medicine (2020)
A smaller number of coexisting mutations, earlier stage, and younger age were associated with longer RFS and OS, while EGFR mutations were significantly associated with improved OS.
Keyphrases
  • epidermal growth factor receptor
  • lymph node
  • tyrosine kinase
  • copy number
  • dna methylation