Regenerative Signatures in Bronchioalveolar Lavage of Acute Respiratory Distress Syndrome.

Runzhen ZhaoMarco HadisuryaHarrison NdetanNan Miles XiSitaramaraju AdduriNagarjun Venkata KonduruBuka SamtenW Andy TaoKaran P SinghHong-Long Ji

Published in: bioRxiv : the preprint server for biology (2023)

This study identifies novel exosomal proteins associated with diverse functions, signaling pathways, and cell origins in ARDS lavage samples. These differentiated proteins may serve as regenerative niches for re-alveolarization in injured lungs.

Keyphrases

acute respiratory distress syndrome
cell therapy
extracorporeal membrane oxygenation
stem cells
mechanical ventilation
mesenchymal stem cells
genome wide
signaling pathway
tissue engineering
single cell
epithelial mesenchymal transition
cell proliferation
pi k akt
bone marrow