A double-blind, controlled, crossover trial of amlodipine on iron overload status in transfusion dependent β-thalassemia patients.
Hossein KaramiHadiseh Khalilzadeh ArjmandiEbrahim SalehifarHadi Darvishi-KhezriMojdeh DabirianMehrnoush KosaryanAily AliasgharianRosetta AkbarzadehRaheleh Naeimayi AaliAmirreza NasirzadehPublished in: International journal of clinical practice (2021)
Amlodipine might improve myocardial MRI T2* and serum ferritin level compared to placebo. However, larger clinical studies are needed to confirm the results.
Keyphrases
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- ejection fraction
- magnetic resonance imaging
- phase iii
- peritoneal dialysis
- clinical trial
- prognostic factors
- double blind
- computed tomography
- sickle cell disease
- cardiac surgery
- patient reported outcomes
- heart failure
- contrast enhanced
- magnetic resonance
- placebo controlled