Efficacy and safety of fibrinogen concentrate for on-demand treatment of bleeding and surgical prophylaxis in paediatric patients with congenital fibrinogen deficiency.

Claudia Djambas KhayatSunil LohadeFulton D'SouzaLatha Gowda ShamanurOmid Reza ZekavatIrina KruzhkovaBruce SchwartzCristina SolomonSigurd KnaubFlora Peyvandi

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2020)

HFC treatment for on-demand treatment of BEs and surgical prophylaxis was efficacious for this ultra-rare paediatric population with congenital afibrinogenaemia and showed a favourable PK and safety profile.

Keyphrases

emergency department
intensive care unit
atrial fibrillation
combination therapy
high resolution
mass spectrometry
smoking cessation