Therapeutic Drug Monitoring of Olanzapine: Effects of Clinical Factors on Plasma Concentrations in Psychiatric Patients.

Nicolas AnsermotHarish VathanarasaSetareh RanjbarMehdi GholamSéverine CrettolFrederik VandenbergheFranziska GammaKerstin Jessica PlessenArmin von GuntenPhilippe ConusChin B Eap

Published in: Therapeutic drug monitoring (2024)

The clinical factors examined in this study, including sex, age, body weight, smoking status, and valproate comedication, remarkably influence olanzapine C:D ratios. Considering these factors, in addition to TDM and the clinical situation, could be important for dose adjustment.

Keyphrases

body weight
end stage renal disease
newly diagnosed
patient reported outcomes
chemotherapy induced