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Facile iodine-promoted synthesis of bis(1-imidazo[1,5- a ]pyridyl)arylmethanes and exploration of applications.

Ban Van PhucNina Thi NguyenNguyen Thi Hong VanThanh Luan NguyenVan Ha NguyenCong Minh TranHien NguyenMinh Tho NguyenTran Quang HungTuan Thanh Dang
Published in: Chemical communications (Cambridge, England) (2023)
A practical strategy for the iodine-promoted synthesis of bis(1-imidazo[1,5- a ]pyridyl)arylmethane and its derivatives has been developed. These compounds exhibit high cytotoxicity toward various cancer cell lines and moreover they are promising ligands for the Cu-catalysed synthesis of quinolines.
Keyphrases
  • papillary thyroid
  • dual energy
  • magnetic resonance imaging
  • squamous cell carcinoma
  • computed tomography
  • highly efficient
  • lymph node metastasis