Homozygous Sickle Cell Disease after Age of 40: Follow-Up of a Cohort of 209 Patients in Senegal, West Africa.

Moussa SeckMaureen Adéniké DaboElimane Seydi BoussoMohamed KeitaSokhna Aïssatou TouréSérigne Mourtalla GuèyeBlaise Félix FayeFatma DiengSaliou Diop

Published in: Advances in hematology (2024)

This study shows that homozygous SCD is increasingly becoming an adult disease and that it can be carried into old age in Africa. Advanced age over 40 is marked by an upsurge in chronic complications, making it essential to set up a screening program and to organize multidisciplinary follow-up.

Keyphrases

sickle cell disease
end stage renal disease
ejection fraction
newly diagnosed
quality improvement
chronic kidney disease
prognostic factors
patient reported outcomes
patient reported