Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis.
Joycilene da Silva BarbosaGeraldo Bezerra da Silva JúniorGdayllon Cavalcante MenesesAlice Maria Costa MartinsElizabeth de Francesco DaherRosângela Pinheiro Gonçalves MachadoRomélia Pinheiro Gonçalves LemesPublished in: Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia (2021)
Acute kidney injury (AKI) is a common finding in Neotatal Intensive Care Units (NICU). Sepsis is one the main causes of AKI in preterm newborns. AKI has been associated with significant death rates. Early detection of the condition is the first step to improving prevention, treatment, and outcomes, while decreasing length of hospitalization, care costs, and morbimortality. AKI may progress to chronic kidney disease (CKD), a condition linked with dialysis and greater risk of cardiovascular disease. This review article aims to discuss cases of AKI in preterm newborns with sepsis, the use of biomarkers in lab workup, and the use of non-conventional biomarkers for the early identification of AKI.
Keyphrases
- acute kidney injury
- low birth weight
- gestational age
- chronic kidney disease
- cardiac surgery
- preterm infants
- preterm birth
- cardiovascular disease
- end stage renal disease
- intensive care unit
- pregnant women
- healthcare
- palliative care
- cord blood
- type diabetes
- metabolic syndrome
- pain management
- mechanical ventilation
- skeletal muscle
- acute respiratory distress syndrome
- quality improvement
- affordable care act
- glycemic control