Intact HIV reservoir in monocytes is associated with cognitive function in virally suppressed women with HIV.

Leah H RubinErin N ShirkLily PohlenzHayley RomeroElizabeth RotiRaha M DastgheybIsabel SantiusteJennifer M CoughlinTodd T BrownJanice E ClementsRebecca T Veenhuis

Published in: The Journal of infectious diseases (2024)

The number of intact HIV genomes per million monocytes were related to poorer cognition and the percentage of intermediate monocytes. These findings suggest that the presence of HIV genomes in general do not relate to cognitive complications, but intact, and therefore potentially replication-competent HIV, may contribute to cognitive complications in vsWWH.

Keyphrases

antiretroviral therapy
hiv positive
hiv infected
hiv testing
human immunodeficiency virus
hepatitis c virus
hiv aids
men who have sex with men
south africa
peripheral blood
risk factors