Cytotoxicity and Mineralization Activity of Calcium Silicate-Based Root Canal Sealers Compared to Conventional Resin-Based Sealer in Human Gingival Fibroblast Cells.

Mohammad Shokrzadeh Farzaneh Sadat Motafeghi Anahita Lotfizadeh Mohammad Ghorbani Azam Haddadi Kohsar

Published in: International journal of dentistry (2023)

The examined calcium silicate-based sealers had less cytotoxicity and higher mineralization activity than the resin-based sealer (AH26). There was negligible difference between the cytotoxicity of the two-calcium silicate-based, but the cell mineralization caused by Endoseal MTA was higher.

Keyphrases

endothelial cells
induced apoptosis
single cell
oxidative stress
signaling pathway
stem cells
cell proliferation
bone marrow